How to interface a current generation Makerbot Extruder controller board to MACH3 to 3d

3D Printing
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1

How to interface a current generation Makerbot Extruder controller board to MACH3 to 3d print on a CNC?
It has been done with older versions of that board.

2

how big of a CNC?

3

400x300
how does that matter?