Yeah, prusa-slicer, and slic3r from whence it came, expose settings for covering a variety of approaches. Most of the time most of us don’t modify a lot of settings. 
The good news is that just getting started doesn’t usually require changing lots of settings. Start with the simple mode, and ask questions here about what individual settings mean.
I’d also suggest starting a separate thread for calibrating/tuning your specific printer, and sharing pictures and measurements. Some of the things you tweak there will be printer-based and some will be slicer-based. (Be aware that the common 20mm XYZ “calibration cube” might be hard to use for tuning; it’s small enough that sometimes different printing artifacts aren’t clearly distinguished. But I think it’s a fine place to start.)